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A Fatal Flaw in the Nutrient-Toxicity Model of Dietetics

New section added. Ingested nutrients are not passively absorbed, but actively and consciously imported through tightly regulated processes that also use stored energy and nitrogen. This section is the first part of an ...
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An Unrecognised Paradox in Nutrition

New chapter added. It covers the mechanism by which over- and under-nutrition relates to pathology, and why the principle of toxicology that states that “the dose makes the poison” can’t be said to ...
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The Biological “Raison d’Être” of Vertebrate Joints and Osteoarthritis

New section added. Four out of every five species of animals seams to have figured out how to avoid premature ageing of their joints, so why haven’t we? This section is still not ...
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Added Charts and Figures

I’ve started to create graphic material to accompany the mechanistic explanations in the Histopathology-chapter. As with everything els in the book, they are a continual work-in-progress and as usual I gladly accept feedback ...
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Gout in a Larger Perspective, and a Peek Into the Complex Nature of Fruits

New section added. Its a short follow-up on the idea of gout being a side-effect of microbial nitrogen acquisition, and how this might be related to the evolution of fruit-production in plants. Perhaps ...
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How Muscular Flexibility Might Predict Blood-Pressure

Is it possible that the same mechanism that causes arteries harden in atherosclerosis is also causing the phenomenon of common muscle-stiffness? A study suggest that this might be the case. The study showed ...
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Core Hypothesis – A Summary

New section added. A short summary of my hypothesis on the origins and pathophysiology of musculoskeletal disease. It is an overview of the core mechanistic interplay that is further outlined in the rest ...
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In Defense of Destructive Inflammation

New section added. Inflammation is a term that many use, but very few actually understand. Because of its endogenous origin and near universal association with disease, it is tempting to jump to reductionistic conclusions ...
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Epidural Lipomatosis – Why some Hernias Hurt more than Others

It has been known for long that a large part of the population have asymptomatic disc-herniations, but why is it that in some cases even minor herniations can cause severe pain? A partial ...
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The Role of Microbes in Health and Disease

New section added. How do we resolve the paradox of microbes being essential for health while at the same time also being the factor that causes or modifies disease-progression in both communicable and ...
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An Ecological Perspective on Pathology

New section added. Can ecological principles make sense of the “why” in chronic disease? In this section I lay out the foundation for my main-hypothesis and a perspective on what I believe disease ...
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Histopathological Similarities in Musculoskeletal Disease

New chapter added. Histopathology. It covers key signs and mechanisms at the cell/tissue-level of musculoskeletal disease, and is an attempt to make a case that we are dealing with conditions that might simply ...
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Diet Is an Independent Causal Variable in Osteoarthritis

A 2016 study by A.Yoshinori et al  divided mice into four groups. Normal loading-pattern with a normal diet (NL+ND), normal loading-pattern with a western-style diet (NL+HFD), tail-suspension with a normal diet (TS+ND) and ...
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Gout, a Not so Non-Infectious Disease

First section added! 130+ references to the scientific literature. Elevated serum uric acid alone has surprisingly never been proven to cause gout. Mycotoxins, a class of fungal secondary metabolites might be the missing ...
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What Is This, and Who Am I?

Hello everyone, and welcome to my website. I’ve put together a text explaining who I am and what my intentions are with this page. It can be found here. If you wish to ...
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